Submit Manuscript  

Article Details


Expeditious Solvent-Free Synthesis of Chromene Derivatives via Three- Component Reactions of N-Nucleophiles

[ Vol. 15 , Issue. 10 ]

Author(s):

Mohammad R. Hosseini-Tabatabaei and Faramarz Rostami-Charati   Pages 835 - 839 ( 5 )

Abstract:


Multicomponent reactions involving 4-hydroxycumarine, activated acetylenic compounds and N-nucleophiles under solvent-free conditions were investigated. The reactions could also be extended to quinoline or CH-acides. Substituted chromen could be obtained from this routine, which may have potential applications in drugs fields.

Keywords:

4-Hydroxy coumarin, acetylenic compounds, isoquinoline, one-pot reactions, solvent-free.

Affiliation:

Department of Chemistry, Zahedan Branch, Islamic Azad University, Zahedan, Iran



Read Full-Text article