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Novel Approach for the Synthesis of Pyrrolo[2,1-c][1,4]Benzoxazines and Pyrrolo[1,2-a]Quinoxalines

[ Vol. 17 , Issue. 2 ]


Tayebeh Sanaeishoar, Somayeh Adibi-Sedeh and Saghar Karimian   Pages 157 - 161 ( 5 )


An efficient synthesis of alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[2,1-c][1,4]benzoxazine-3-carboxylates and alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[1,2-a]quinoxaline-3-carboxylates is described. This involves a three-component reaction between o-aminophenols or o-phenylenediamine, acetylenic esters and β-nitrostyrene derivatives using p-toluene sulfonic acid as a catalyst.


o-aminophenols, o-phenylenediamine, p-toluene sulfonic acid, pyrrolo[1, 2-a]quinoxaline, pyrrolo[2, 1-c][1, 4]benzoxazine, β- nitrostyrenes.


Chemistry Department, Science and Research Branch, Islamic Azad University, Khouzestan, Iran.

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