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Organocatalytic Combinatorial Synthesis of Quinazoline, Quinoxaline and Bis(indolyl)methanes

Author(s):

Fatemeh Malamiri, Samad Khaksar*, Rashid Badri and Elham Tahanpesar   Pages 1 - 7 ( 7 )

Abstract:


Aim and Objective: An efficient and practical procedure for the synthesis of heterocyclic compounds such as quinazolines, quinoxalines and bis(indolyl)methanes was developed using 3,5-bis(trifluoromethyl) phenyl ammonium hexafluorophosphate (BFPHP) as a novel organocatalyst.

Materials and Methods: All of the obtained products are known compounds and identified by IR, 1HNMR,13CNMR and melting points.

Result: Various products were obtained in good to excellent yields under reaction conditions

Conclusion: The BFPHP organocatalyst demonstrates a novel class of non-asymmetric organocatalysts, which has gained much attention in green chemistry.

Keywords:

Organocatalyst, Green Chemistry, Quinazoline, Multicomponent, Heterocyclic, Anticancer

Affiliation:

Department of Chemistry, Khouzestan Science and Research Branch, Islamic Azad University, Ahvaz, Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz



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