Ayse Ozcan-Kucuk*, Bilal Ege, Mahmut Koparal, Ataman Gonel and Ismail Koyuncu Pages 1 - 9 ( 9 )
Aims and Objective: Sleep bruxism is a complicated disease, and its cause remains controversial.If the aetiology of bruxism is resolved, the treatment can be adjusted to the prevailing aetiological factor.Thus,the aim of this study was to evaluate the oxidative stress level and serum prolidase activity in patients with sleep bruxism.
Materials and Methods: Seventy healthy subjects and 51 patients with sleep bruxism were included in this study, and blood samples from all patients were collected. Serum samples were analysed for total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) and prolidase activity.
Results: The prolidase,TOS and OSI levels were significantly higher in patients with bruxism than in the healthy controls (p = 0.001, p = 0.001, p = 0.001, respectively). The TAS level was significantly lower in bruxism patientsthan in the healthy controls (p = 0.003).
Conclusion: The increased TOS, OSI and prolidase levels and decreased TAS levels could be assumed to result in oxidative injury in patients with sleep bruxism. However, the study could not determine whether oxidative imbalance and increased serum prolidase levels could be a cause or a result of bruxism.
Bruxism, prolidase activity, oxidative stress, antioxidant, oxidant system, oxidative status
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mersin University, Mersin, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Department of Bio-chemistry, Faculty of Medicine, Harran University, Şanlıurfa, Department of Bio-chemistry, Faculty of Medicine, Harran University, Şanlıurfa