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Cell Interactions with Biomaterials Gradients and Arrays

[ Vol. 12 , Issue. 6 ]


Carl G. Simon Jr., Yanyin Yang, Vinoy Thomas, Shauna M. Dorsey and Abby W. Morgan   Pages 544 - 553 ( 10 )


Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.


Biomaterials, cell adhesion, cell-material interactions, combinatorial screening, gradient, hydrogel, microarray, polymer, tissue engineering


Polymers Division, National Institute of Standards&Technology, 100 Bureau Drive, Gaithersburg, MD 20899-8545, USA.

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